RGFP966 | 2818

RGFP966 is a potent and selective histone deacetylase 3 (HDAC3) inhibitor (IC₅₀ = 80 nM). It does not inhibit other HDACs at concentrations up to 15 µM.

RGFP966 is a potent and selective histone deacetylase 3 (HDAC3) inhibitor (IC₅₀ = 80 nM). It does not inhibit other HDACs at concentrations up to 15 µM.

2818 | RGFP966 DataSheet

Alternate Name/Synonyms: (E)-N-(2-Amino-4-fluorophenyl)-3-[1-[(E)-3-phenylprop-2-enyl]pyrazol-4-yl]prop-2-enamide

Appearance: White solid

Formulation: N/A

CAS Number: 1396841-57-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₁₉FN₄O

Molecular Weight: 362.4

Cell-Permeable?: yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective histone deacetylase 3 (HDAC3) inhibitor

MDL Number: N/A

PubChem CID: 56650312

SMILES: C1=CC=C(C=C1)C=CCN2C=C(C=N2)C=CC(=O)NC3=C(C=C(C=C3)F)N

InChi: InChI=1S/C21H19FN4O/c22-18-9-10-20(19(23)13-18)25-21(27)11-8-17-14-24-26(15-17)12-4-7-16-5-2-1-3-6-16/h1-11,13-15H,12,23H2,(H,25,27)/b7-4+,11-8+

InChi Key: BLVQHYHDYFTPDV-VCABWLAWSA-N