RGS1 Polyclonal Antibody | E-AB-11534

RGS1 Polyclonal Antibody | E-AB-11534 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 1R20, B cell activation protein BL34, B-cell activation protein BL34, BL34, Early response protein 1R20, IER 1, IER1, Immediate early response 1 B cell specific, immediate-early response 1, B-cell specific, IR20, Regulator of G protein signalling 1, Regulator of G-protein signaling 1, RGS 1, RGS1, RGS1

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human RGS1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 24 kDa

Molecular Weight(Observed): N/A