RGS14 polyclonal Antibody | BS61912

RGS14 polyclonal Antibody | BS61912 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: IHC

Application Range: IHC: 1:50~1:200

Background: RGS domains bind directly to activated Ga subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Ga-GTP and Gbg. RGS proteins shorten the lifetime of the activated G protein. Western blot analysis shows strong expression of RGS14 as a primarily cytosolic protein restricted to brain and spleen. It is suggested that RGS14 may constitute a bridging molecule that allows cross-regulation of signaling pathways downstream from G protein-coupled receptors.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RGS14 polyclonal Antibody detects endogenous levels of RGS14 protein.

Molecular Weight: ~ 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Regulator of G-protein signaling 14

Immunogen: Synthetic peptide, corresponding Human RGS14.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: