RGS3 Antibody (N-Term) [AMM07599G]

RGS3 Antibody (N-Term) [AMM07599G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This RGS3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 273-307 amino acids from human RGS3.

Cellular Localisation: Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Note=Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594) . Short isoforms are nuclear (PubMed:10749886)

Molecular Weight: 132336

Clone: Polyclonal

Gene Name: RGS3

Gene ID: 5998

Function: Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein- mediated release of inositol phosphates and activation of MAP kinases.

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Regulator of G-protein signaling 3, RGP3, RGS3, RGS3