800
Rhodopsin Antibody (RHO)| F45215-0.08ML
- SKU:
- 800-F45215-0.08ML
- Availability:
- Usually ships in 5 working days
Description
Rhodopsin Antibody (RHO)| F45215-0.08ML | Gentaur UK, US & Europe Distribution
Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form, which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Isotype: Rabbit Ig
Species Reactivity: Human
Predicted Spacies Reactivity: Primate
Application: WB, ELISA
Application Details: Western blot: 1:1000
Application Note: Titration of the RHO antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Status: Available
Buffer: N/A
Limitation: This RHO antibody is available for research use only.
Purity: Antigen affinity
Immunogen: A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.
Storage: Aliquot the RHO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Localization: N/A