RHOH monoclonal Antibody | MB64922

RHOH monoclonal Antibody | MB64922 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:2000

Background: The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP) -metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: ras homolog family member H

Molecular Weight: 21.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ARHH; TTF

Immunogen: Human recombinant protein fragment corresponding to amino acids 97-190 of human RHOH (NP_004301) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A