RICTOR Polyclonal Antibody | E-AB-10904

RICTOR Polyclonal Antibody | E-AB-10904 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AVO3, AVO3 homolog, DKFZp686B11164, hAVO3, KIAA1999, Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae), mAVO3, MGC39830, PIA, Pianissimo, Rapamycin insensitive companion of mTOR, Rapamycin-insensitive companion of mTOR, Rictor, RICTR, RICTR, RPTOR independent companion of MTOR complex 2, TORC2 specific protein AVO3

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Signal Transduction

Background: Rapamycin-insensitive companion of mTORis aproteinthat in humans is encoded by theRICTORgene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human RICTOR

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A