RNASE1 Polyclonal Antibody | E-AB-19132

RNASE1 Polyclonal Antibody | E-AB-19132 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: HP-RNase, Pancreatic ribonuclease, Rib 1, RIB-1, Rib1, Ribonuclease 1, Ribonuclease A, Ribonuclease a family 1, Ribonuclease pancreatic, Ribonuclease RNase A family 1, Ribonuclease RNase A family 1 pancreatic, RNAS1_HUMAN, RNase 1, RNase A, RNase UpI-1, Rnase1, RNAseA

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2', 3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human RNASE1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 18 kDa

Molecular Weight(Observed): Refer to figures