Description
RNASE1 Polyclonal Antibody | E-AB-19132 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: HP-RNase, Pancreatic ribonuclease, Rib 1, RIB-1, Rib1, Ribonuclease 1, Ribonuclease A, Ribonuclease a family 1, Ribonuclease pancreatic, Ribonuclease RNase A family 1, Ribonuclease RNase A family 1 pancreatic, RNAS1_HUMAN, RNase 1, RNase A, RNase UpI-1, Rnase1, RNAseA
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling
Background: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2', 3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Concentration: 0.9 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human RNASE1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 18 kDa
Molecular Weight(Observed): Refer to figures