RNF144B (IBRDC2) monoclonal Antibody | MB64946

RNF144B (IBRDC2) monoclonal Antibody | MB64946 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:100

Background: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: ring finger protein 144B

Molecular Weight: 33.7 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: bA528A10.3; IBRDC2; p53RFP; PIR2

Immunogen: Human recombinant protein fragment corresponding to amino acids 1-256 of human RNF144B (NP_877434) produced in E. coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A