RNF217 Antibody (N-term) [APR31644G]

RNF217 Antibody (N-term) [APR31644G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This RNF217 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human RNF217.

Cellular Localisation: Membrane; Single-pass membrane protein. Cytoplasm

Molecular Weight: 59372

Clone: Polyclonal

Gene Name: RNF217

Gene ID: 154214

Function: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis.

Summary: Tissue Location: Mainly expressed in testis and skeletal muscle.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Probable E3 ubiquitin-protein ligase RNF217, 632-, IBR domain-containing protein 1, RING finger protein 217, RNF217, C6orf172, IBRDC1