RNH1 (Ribonuclease Inhibitor) monoclonal Antibody | MB64955

RNH1 (Ribonuclease Inhibitor) monoclonal Antibody | MB64955 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Rat, Dog

Application: FC, IHC, WB

Application Range: WB 1:500~2000, FLOW 1:100, IHC: 1:150

Background: Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]) . In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850) . Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo. [supplied by OMIM]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: ribonuclease/angiogenin inhibitor 1

Molecular Weight: 49.8 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RAI; RNH

Immunogen: Full length human recombinant protein of human RNH1 (NP_002930) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A