Description
ROR2 Antibody [APR14392G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ROR2 antibody is generated from rabbits immunized with a recombinant protein of human ROR2.
Cellular Localisation: Cell membrane; Single-pass type I membrane protein
Molecular Weight: 104757
Clone: Polyclonal
Gene Name: ROR2
Gene ID: 4920
Function: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity) . Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073) . In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Tyrosine-protein kinase transmembrane receptor ROR2, Neurotrophic tyrosine kinase, receptor-related 2, ROR2, NTRKR2