Roscovitine | 1950

Cell-permeable. A potent inhibitor of p34cdc2 (IC₅₀ = 0.2 µM). Also inhibits p33cdk2 and p33cdk5.

Roscovitine is a potent inhibitor of p34cdc2 (IC₅₀ = 0.2 µM). Also inhibits p33cdk2 and p33cdk5.

1950 | Roscovitine DataSheet

Alternate Name/Synonyms: 6-Benzylamino-2[(R)-(1'-ethyl-2'-hydroxyethylamino)]-9-isopropylpurine; CYC202; Seliciclib

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 186692-46-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₆N₆O

Molecular Weight: 354.45

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~200 mg/ml) or EtOH (~ 200 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent inhibitor of p34cdc2

MDL Number: MFCD02266401

PubChem CID: 160355

SMILES: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C

InChi: InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1

InChi Key: BTIHMVBBUGXLCJ-OAHLLOKOSA-N