Rosuvastatin . calcium salt | 10-041

Rosuvastatin . calcium salt | 10-041 | Gentaur UK, US & Europe Distribution

BNR: Chemical

Predicted Molecular Weight: 480.6 . 20.0

Physical State: Lyophilized

Storage Condition: Short Term Storage: +4C. Long Term Storage: -20C. Handling Advice: Keep cool and dry. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.

Alternate Name: Crestor

Background: Rosuvastatin is a potent competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering drugs. Rosuvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. Formulations containing rosuvastatin reduce low-density lipoprotein (LDL) and C-reactive protein and increase high-density lipoprotein (HDL) in humans. Shown to have anti-inflammatory, antioxidant, antithrombotic and insulin sensitizing properties. Identified as a potential inhibitor of SARS-CoV-2, responsible for COVID-19.

Disclaimer: This product is for research use only.

Purity: greater than or equal to 98% (HPLC)

Formula: C22H27FN3O6S . 1/2Ca

Source: N/A

Solubility: Soluble in DMSO or ethanol. Insoluble in water.

InChi Key: VGAZDTHGPVFCCO-YFRSHGDPSA-K

Smiles: CN (S (C) (=O) =O) C1=NC (C2=CC=C (F) C=C2) =C (/C=C/[C@H] (C[C@@H] (O) CC ([O-]) =O) O) C (C (C) C) =N1.[Ca+2]

RTECS: MJ9675070

Identity: Determined by 1H-NMR.

Merck Index: N/A