LBD
RPGRIP1 Antibody (Center) [APR13147G]
- SKU:
- LBD-APR13147G
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- Usually ships in 5 working days
Description
RPGRIP1 Antibody (Center) [APR13147G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This RPGRIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-557 amino acids from the Central region of human RPGRIP1.
Cellular Localisation: Cell projection, cilium. Note=Situated between the axonemal microtubules and the plasma membrane (By similarity) . In the retinal photoreceptor cell layer, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (By similarity) . Colocalizes with RGPR in the photoreceptor connecting cilium (By similarity) . {ECO:0000250|UniProtKB:Q9EPQ2}
Molecular Weight: 146682
Clone: Polyclonal
Gene Name: RPGRIP1
Gene ID: 57096
Function: May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells.
Summary: Tissue Location: Strong expression in retina, with weaker expression in testis. Expressed in other neurons such as amacrine cells Colocalizes with RGPR in the outer segment of rod photoreceptors and cone outer segments.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: X-linked retinitis pigmentosa GTPase regulator-interacting protein 1, RPGR-interacting protein 1, RPGRIP1