RRAGA Polyclonal Antibody | E-AB-15366

RRAGA Polyclonal Antibody | E-AB-15366 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1, Rag A, RagA, Ras-related GTP-binding protein A, RRAGA, RRAGA

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Metabolism, Microbiology, Signal Transduction

Background: Ras-related GTP-binding protein Ais aproteinthat in humans is encoded by theRRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human RRAGA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 37 kDa

Molecular Weight(Observed): N/A