Description
RRM1 Antibody | 14-936 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_001024.1) .
Research Area: Other
Tested Application: WB, IF, IP
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: SW480
Positive Control 3: 22Rv1
Positive Control 4: U-251MG
Positive Control 5: Mouse thymus
Positive Control 6: Mouse testis
Molecular Weight: Observed: 95kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: RRM1, R1, RIR1, RR1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.