RRM1 Polyclonal Antibody | E-AB-14316

RRM1 Polyclonal Antibody | E-AB-14316 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: R1, Ribonucleoside diphosphate reductase large subunit, Ribonucleoside diphosphate reductase M1 chain, Ribonucleoside diphosphate reductase subunit M1, Ribonucleoside reductase, large subunit, Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large chain, Ribonucleotide reductase large subunit, Ribonucleotide reductase M1, Ribonucleotide reductase M1 polypeptide, Ribonucleotide reductase R1 subunit, Ribonucleotide reductase, M1 subunit, RIR 1, RIR1, RIR1, RR 1, RR1, RRM 1, RRM1

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human RRM1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 90 kDa

Molecular Weight(Observed): N/A