RSK1 p90 (Phospho-T359/S363) polyclonal Antibody | BS94048

RSK1 p90 (Phospho-T359/S363) polyclonal Antibody | BS94048 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC IP

Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. The family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase β, which are thought to have similar regulatory functions. MSK1 (also designated RLPK) is a novel Rsk-related protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: RSK1 p90 (Phospho-T359/S363) polyclonal Antibody detects endogenous levels of RSK1 p90 protein only when phosphorylated at T359/S363.

Molecular Weight: 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: S6K-alpha-1, p90-RSK 1, p90RSK1, p90S6K, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, RSK-1, RPS6KA1, 90 kDa ribosomal protein S6 kinase 1, dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1, dJ590P13.1, EC 2.7.11.1, HU 1, HU1, KS6A1, MAP kinase activated protein kinase 1a, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, MAPKAPK1A, MGC79981, Mitogen-activated protein kinase-activated protein kinase 1A, OTTHUMP00000004113, p90 RSK1, p90-RSK 1, p90rsk, p90RSK1, p90S6K, pp90RSK1, Ribosomal protein S6 kinase 90kD 1, Ribosomal protein S6 kinase 90kD polypeptide 1, Ribosomal protein S6 kinase 90kDa polypeptide 1, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase alpha-1, Ribosomal protein S6 kinase polypeptide 1, Ribosomal S6 kinase 1, RPS6K1 alpha, rps6ka, Rps6ka1, RSK 1, RSK 1 p90, RSK, RSK-1, RSK1, S6K alpha 1, S6K-alpha-1,

Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Thr359 and Ser363 of human RSK1 p90

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: ProA affinity purified

Pathway: