RTA-402 | B1974

RTA-402 is a synthetic triterpenoid compound with anti-inflammatory, antitumor and cytoprotective properties. RTA-402 is a potent nuclear factor erythroid 2-related factor 2 (Nrf2) activator. CDDO-Me has been used for the treatment of chronic kidney disease, cancer (including leukemia and solid tumors), and other diseases.

RTA-402 is a synthetic triterpenoid compound with anti-inflammatory, antitumor and cytoprotective properties. RTA-402 is a potent nuclear factor erythroid 2-related factor 2 (Nrf2) activator. CDDO-Me has been used for the treatment of chronic kidney disease, cancer (including leukemia and solid tumors), and other diseases.

B1974 | RTA-402 DataSheet

Alternate Name/Synonyms: Bardoxolone methyl; CDDO Methyl ester; CDDOMe; NSC 713200; RTA402

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 218600-53-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₂H₄₃NO₄

Molecular Weight: 505.69

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent nuclear factor erythroid 2-related factor 2 (Nrf2) activator

MDL Number: MFCD11983137

PubChem CID: 400769

SMILES: CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)C(=O)OC)C

InChi: InChI=1S/C32H43NO4/c1-27(2)11-13-32(26(36)37-8)14-12-31(7)24(20(32)17-27)21(34)15-23-29(5)16-19(18-33)25(35)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3/t20-,22-,24-,29-,30+,31+,32-/m0/s1

InChi Key: WPTTVJLTNAWYAO-KPOXMGGZSA-N