RUFY3 Polyclonal Antibody | E-AB-64364

RUFY3 Polyclonal Antibody | E-AB-64364 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: RUFY3, RIPX, SINGAR1, ZFYVE30

Application: WB

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human RUFY3 (NP_055776.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 52 kDa/55 kDa/64 kDa/70 kDa

Molecular Weight(Observed): 56 kDa