RUNX1 Antibody | 28-784

RUNX1 Antibody | 28-784 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, Dog

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RUNX1.

Research Area: Transcription, Cancer

Tested Application: E, WB

Application: RUNX1 antibody can be used for detection of RUNX1 by ELISA at 1:12500. RUNX1 antibody can be used for detection of RUNX1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1205 - Jurkat Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 12 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by peptide affinity chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store RUNX1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: RUNX1, AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia.