RYR1 Polyclonal Antibody | E-AB-13584

RYR1 Polyclonal Antibody | E-AB-13584 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CCO, Central core disease of muscle, MHS, MHS1, PPP1R137, Protein phosphatase 1 regulatory subunit 137, Ryanodine receptor 1, RYDR, RYR, RYR-1, RyR1, RYR1, sarcoplasmic reticulum calcium release channel, Skeletal muscle calcium release channel, Skeletal muscle ryanodine receptor, Skeletal muscle-type ryanodine receptor, SKRR, Type 1 ryanodine receptor

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience

Background: This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human RYR1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 565 kDa

Molecular Weight(Observed): N/A