RYR2 polyclonal Antibody | BS91191

RYR2 polyclonal Antibody | BS91191 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500 ICC:1:50-1:100 IHC:1:50-1:200 FC:1:50-1:100

Background: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: RYR2 polyclonal Antibody detects endogenous levels of RYR2 protein.

Molecular Weight: 565 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RYR-2, RyR2, hRYR-2, RYR2, Arrhythmogenic right ventricular dysplasia 2, ARVC2, ARVD2, Brain ryanodine receptor calcium release channel, Brain type ryanodine receptor, Cardiac muscle ryanodine receptor calcium release channel, Cardiac muscle type ryanodine receptor, CCO, Central core disease of muscle, HBRR, hRYR 2, hRYR2, MHS, MHS1, Ryanodine receptor 1 (skeletal), Ryanodine receptor 1, Ryanodine receptor 2 (cardiac), Ryanodine receptor 2, Ryanodine receptor 3, Ryanodine receptor type1, RYDR, RYR 1, RYR 2, RYR 3, RYR, RYR-1, RyR1, RYR1, RYR2, RYR3, Sarcoplasmic reticulum calcium release channel, Skeletal muscle calcium release channel, Skeletal muscle ryanodine receptor, Skeletal muscle type ryanodine receptor, Skeletal muscle-type ryanodine receptor, SKRR, Type 1 like ryanodine receptor, Type 1 ryanodine receptor, VTSIP,

Immunogen: Synthetic peptide within human RYR2 aa 1450-1550.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified.

Pathway: