(S)-Duloxetine hydrochloride | B2680

(S)-Duloxetine hydrochloride belongs to the class of serotonin and norepinephrine reuptake inhibitors. (S)-Duloxetine suppresses spontaneous firing activity in vivo in the dorsal raphe and locus coeruleus (ED50s = 99 and 475 µg/kg, respectively). It is used to treat stress urinary incontinence, psychiatric and metabolic disorders. It is also used for treating diabetic peripheral neuropathic pain, fibromyalgia, chronic musculoskeletal and low back pain (LBP).

(S)-Duloxetine hydrochloride belongs to the class of serotonin and norepinephrine reuptake inhibitors. (S)-Duloxetine suppresses spontaneous firing activity in vivo in the dorsal raphe and locus coeruleus (ED50s = 99 and 475 µg/kg, respectively). It is used to treat stress urinary incontinence, psychiatric and metabolic disorders. It is also used for treating diabetic peripheral neuropathic pain, fibromyalgia, chronic musculoskeletal and low back pain (LBP).

B2680 | (S)-Duloxetine hydrochloride DataSheet

Alternate Name/Synonyms: (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride,Duloxetine HCl,Cymbalta

Appearance: White to off-white solid

Formulation:

CAS Number: 136434-34-9

Structure Available?: TRUE

Peptide sequence: N/A

Salt Form: FALSE

Molecular Formula: C18H19NOS • HCl

Molecular Weight: 333.88

Cell-Permeable?: TRUE

Purity: ≥97% by HPLC

Solubilities: ~ 25 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A serotonin and norepinephrine reuptake inhibitor

MDL Number: MFCD06407958

PubChem CID: 60834

SMILES: CNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl

InChi: InChI=1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1

InChi Key: BFFSMCNJSOPUAY-LMOVPXPDSA-N