S100A1 Antibody| F41686-0.08ML/F41686-0.4ML/V3393-100UG/V3393-20UG/V3504IHC-7ML

S100A1 Antibody| F41686-0.08ML/F41686-0.4ML/V3393-100UG/V3393-20UG/V3504IHC-7ML | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Bovine

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:50-1:100

Application Note: Titration of the S100A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This S100A1 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 45-75 from the human protein was used as the immunogen for this S100A1 antibody.

Storage: Aliquot the S100A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A