SAA1 polyclonal Antibody | BS6727

SAA1 polyclonal Antibody | BS6727 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,Rat

Application: WB,IHC

Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Background: The serum amyloid A (SAA) family of proteins is encoded by multiple genes, which display allelic variation and a high degree of homology in mammals. The four members of the SAA gene family are clustered on human chromosome 11p15.1. Three SAA genes are differentially expressed and encode small apolipoproteins. SAA1 and SAA2 encode the acute phase SAAs (A-SAAs), and SAA4 encodes the constitutively expressed SAA (C-SAA) . A fourth locus, SAA3 is a pseudogene that contains two C/EBP-binding sites and a third site, which interacts with SAA3 enhancer factor. Human SAA proteins are a group of apolipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma. SAA is a major acute-phase protein and precursor to amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis. SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SAA1 polyclonal Antibody detects endogenous levels of SAA1 protein.

Molecular Weight: ~ 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Amyloid fibril protein AA; Amyloid fibrils; Amyloid protein A; Fibrils; MGC111216; OC; PIG 4; PIG4; SAA 1; SAA 2; SAA; SAA; SAA1; SAA2; Serum amyloid A protein precursor; Serum amyloid A1 isoform 1; Serum amyloid A1 isoform 2; Serum amyloid protein A (4-101) ; TP53I4; Tumor protein p53 inducible protein 4;

Immunogen: Recombinant full length Human SAA1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: