SAE2/UBA2 polyclonal Antibody | BS91200

SAE2/UBA2 polyclonal Antibody | BS91200 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IP

Application Range: WB: 1:500 IP:1:10-1:50

Background: The small ubiquitin-related modifier protein SUMO-1 belongs to the ubiquitin-like protein family, which are synthesized as precursor proteins that undergo processing before conjugation to target proteins. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processes, including nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO-1 utilizes homologues of the E1 and E2 enzymes for conjugation to proteins, which include IkBα, MDM2, p53, PML, and RanGap1. AOS1 is homologous to the N-terminal half of E1 and UBA2 is homologous to the C-terminal half of E1. These proteins form a heterodimer that activates SUMO-1.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SAE2/UBA2 polyclonal Antibody detects endogenous levels of SAE2/UBA2 protein.

Molecular Weight: ~ 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: UBA2, SAE2, UBLE1B, HRIHFB2115, Anthracycline associated resistance ARX, Anthracycline-associated resistance ARX, ARX, FLJ13058, HRIHFB2115, SAE 2, SAE2, SAE2, SUMO 1 activating enzyme subunit 2, SUMO activating enzyme subunit 2, SUMO-activating enzyme subunit 2, UBA2, UBA2 ubiquitin activating enzyme E1 homolog, Ubiquitin like 1 activating enzyme E1B, Ubiquitin like modifier activating enzyme 2, Ubiquitin-like 1-activating enzyme E1B, UBLE1B,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: