Description
Salinomycin is a polyether ionophore antibiotic that has recently been identified as an antitumor drug for several types of cancer stem cell (CSC) treatments. Salinomycin inhibits the migration and invasion of liver cancer stem cells (LCSCs) through the dephosphorylated FAK and ERK1/2 pathways.
Salinomycin is a polyether ionophore antibiotic that has recently been identified as an antitumor drug for several types of cancer stem cell (CSC) treatments. Salinomycin inhibits the migration and invasion of liver cancer stem cells (LCSCs) through the dephosphorylated FAK and ERK1/2 pathways.
B1584 | Salinomycin Sodium DataSheet
Alternate Name/Synonyms: (R)-2-((2R,5S,6R)-6-((2S,3S,4S,6R)-6-((2S,5S,7R,9S,10S,12R,15R)-2-((2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-
Appearance: White to of-white solid
Formulation: N/A
CAS Number: 55721-31-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₄₂H₆₉O₁₁. Na
Molecular Weight: 772.98
Cell-Permeable?: yes
Purity: ≥850U/mg
Solubilities: DMSO (~5 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A cancer stem cell inhibitor
MDL Number: MFCD00036900
PubChem CID: 23703990
SMILES: CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)[O-].[Na+]
InChi: InChI=1S/C42H70O11.Na/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33;/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47);/q;+1/p-1/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-;/m0./s1
InChi Key: YPZYGIQXBGHDBH-UZHRAPRISA-M
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |