SAR-20347 | B1290

SAR-20347 is a novel specific dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2), inhibiting JAK1- and/or TYK2-dependent signaling from the IL-12/IL-23, IL-22, and IFN-alpha receptors.

SAR-20347 is a novel specific dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2), inhibiting JAK1- and/or TYK2-dependent signaling from the IL-12/IL-23, IL-22, and IFN-alpha receptors.

B1290 | SAR-20347 DataSheet

Alternate Name/Synonyms: 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1450881-55-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₁₈ClFN₄O₄

Molecular Weight: 444.84

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A novel specific dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2)

MDL Number: N/A

PubChem CID: 71727668

SMILES: C1COCCN1C(=O)C2=CC=C(C=C2)NC3=C(N=C(O3)C4=C(C=CC=C4Cl)F)C(=O)N

InChi: InChI=1S/C21H18ClFN4O4/c22-14-2-1-3-15(23)16(14)19-26-17(18(24)28)20(31-19)25-13-6-4-12(5-7-13)21(29)27-8-10-30-11-9-27/h1-7,25H,8-11H2,(H2,24,28)

InChi Key: HEDPDFHTQKEORT-UHFFFAOYSA-N