SARS-CoV-2 N Antigen ELISA; 1 step and 1 hr | 568-T3237

Product Overview: Coronaviruses are enveloped viruses with a positive-sense RNA genome and a nucleocapsid of helical symmetry. Coronavirus nucleoproteins (NP) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus infected primary cells and cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein. It is involved in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic marker.

Shipping/Storage Temperature: ship and store at 4°C

Shelf Life: 12 months