SARS virus PUP3 Antibody (C-term) [APR30514G]

SARS virus PUP3 Antibody (C-term) [APR30514G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: S

Specificity: This SARS virus PUP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of SARS virus PUP3.

Cellular Localisation: Host endoplasmic reticulum membrane. Host Golgi apparatus membrane. Host cytoplasm. Note=Localizes to virus- induced vesicular structures called double membrane vesicles

Molecular Weight: 7527

Clone: Polyclonal

Gene Name: 6

Gene ID: 1489673

Function: Disrupts cell nuclear import complex formation by tethering karyopherin alpha 2 and karyopherin beta 1 to the membrane. Retention of import factors at the ER/Golgi membrane leads to a loss of transport into the nucleus. Thereby prevents STAT1 nuclear translocation in response to interferon signaling, thus blocking the expression of interferon stimulated genes (ISGs) that display multiple antiviral activities.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: N/A

Dilution: N/A

Synonyms: Non-structural protein 6, ns6, Accessory protein 6, Protein X3