SARS virus PUP6 Antibody (N-term) [APR30517G]

SARS virus PUP6 Antibody (N-term) [APR30517G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: S

Specificity: This SARS virus PUP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of SARS virus PUP6.

Cellular Localisation: Virion. Host cytoplasmic vesicle membrane; Peripheral membrane protein. Host cytoplasm. Host endoplasmic reticulum. Host nucleus. Host mitochondrion. Note=Binds non-covalently to intracellular lipid bilayers

Molecular Weight: 10802

Clone: Polyclonal

Gene Name: 9b

Gene ID: 1489679

Function: Plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS. Mechanistically, usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6. In addition, causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin- like protein 1/DNM1L.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: N/A

Dilution: N/A

Synonyms: Protein 9b, Accessory protein 9b, ORF-9b, 9b