SAV1 Polyclonal Antibody | E-AB-19264

SAV1 Polyclonal Antibody | E-AB-19264 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 1700040G09Rik, 45 kDa WW domain protein, hWW 45, hWW45, Protein salvador homolog 1, salvador family WW domain containing protein 1, salvador homolog 1 (Drosophila), Salvador homolog 1, Salvador, Drosophila, homolog of, SAV 1, SAV, SAV1, SAV1, WW 45, WW domain containing, WW domain-containing adaptor 45, WW domain-containing protein, 45-KD, WW45, WW45 protein, WWP 4, WWP4

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal transduction

Background: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

Concentration: 1.32 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human SAV1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A