SC-514 | 2442

A reversible, competitive inhibitor of IKK2 (IC₅₀ = 11.2 µM). Does not inhibit other IKK isoforms, or other kinases. Displays dose-dependent inhibition of the transcription of NK-κB dependent genes in cell culture.

SC-514 is a reversible, competitive inhibitor of IKK2 (IC₅₀ = 11.2 µM).

2442 | SC-514 DataSheet

Alternate Name/Synonyms: 5-(Thien-3-yl)-3-aminothiophene-2-carboxamide

Appearance: Yellow solid

Formulation: N/A

CAS Number: 354812-17-2

Structure Available?: Yes

Peptide sequence: No

Salt Form: No

Molecular Formula: C₉H₈N₂OS₂

Molecular Weight: 224.3

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (~25 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A reversible, competitive inhibitor of IKK2

MDL Number: MFCD00206459

PubChem CID: 2807869

SMILES: C1=CSC=C1C2=CC(=C(S2)C(=O)N)N

InChi: InChI=1S/C9H8N2OS2/c10-6-3-7(5-1-2-13-4-5)14-8(6)9(11)12/h1-4H,10H2,(H2,11,12)

InChi Key: BMUACLADCKCNKZ-UHFFFAOYSA-N