SC65 Antibody (C-term) [APR03794G]

SC65 Antibody (C-term) [APR03794G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SC65 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human SC65.

Cellular Localisation: Endoplasmic reticulum

Molecular Weight: 50381

Clone: Polyclonal

Gene Name: P3H4 (HGNC:16946)

Gene ID: 10609

Function: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.

Summary: Tissue Location: Detected in fibroblasts (at protein level) (PubMed:23959653) . Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart (PubMed:10952778)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Synaptonemal complex protein SC65, Leprecan-like protein 4, Nucleolar autoantigen No55, LEPREL4, NOL55, SC65