SCCPDH Polyclonal Antibody | E-AB-19034

SCCPDH Polyclonal Antibody | E-AB-19034 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CGI 49, CGI49, FLJ43187, Probable saccharopine dehydrogenase, Saccharopine dehydrogenase, SCCPDH, SCPDH

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Signal Transduction

Background: SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C.elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3, 000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Concentration: 1.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human SCCPDH

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 47 kDa

Molecular Weight(Observed): Refer to figures