SCH-28080 | B3311

SCH-28080 is a potent H+, K+-ATPase inhibitor (IC50 = 20 nM); binds to the K+ recognition site and is competitive with respect to K+. Inhibits gastric acid secretion in vitro and in vivo.

SCH-28080 is a potent H+, K+-ATPase inhibitor (IC50 = 20 nM); binds to the K+ recognition site and is competitive with respect to K+. Inhibits gastric acid secretion in vitro and in vivo.

B3311 | SCH-28080 DataSheet

Alternate Name/Synonyms: 2-methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile

Appearance: Beige solid

Formulation:

CAS Number: 76081-98-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₅N₃O

Molecular Weight: 277.32

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: >5 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A H+,K+-ATPase inhibitor

MDL Number: MFCD00834620

PubChem CID: 108137

SMILES: CC1=C(N2C=CC=C(C2=N1)OCC3=CC=CC=C3)CC#N

InChi: InChI=1S/C17H15N3O/c1-13-15(9-10-18)20-11-5-8-16(17(20)19-13)21-12-14-6-3-2-4-7-14/h2-8,11H,9,12H2,1H3

InChi Key: PYKJFEPAUKAXNN-UHFFFAOYSA-N