SCO1 Antibody (Center) [APR33280G]

SCO1 Antibody (Center) [APR33280G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SCO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 125-158 amino acids from the Central region of human SCO1.

Cellular Localisation: Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein

Molecular Weight: 33814

Clone: Polyclonal

Gene Name: SCO1

Gene ID: 6341

Function: Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2) . Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT- CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu (A) site on MT-CO2/COX2 (PubMed:15659396, PubMed:16735468, PubMed:17189203, PubMed:19336478, PubMed:15229189) . Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (By similarity) .

Summary: Tissue Location: Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Protein SCO1 homolog, mitochondrial, SCO1, SCOD1