LBD
SCO1 Antibody (Center) [APR33280G]
- SKU:
- LBD-APR33280G
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Description
SCO1 Antibody (Center) [APR33280G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SCO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 125-158 amino acids from the Central region of human SCO1.
Cellular Localisation: Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein
Molecular Weight: 33814
Clone: Polyclonal
Gene Name: SCO1
Gene ID: 6341
Function: Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2) . Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT- CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu (A) site on MT-CO2/COX2 (PubMed:15659396, PubMed:16735468, PubMed:17189203, PubMed:19336478, PubMed:15229189) . Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (By similarity) .
Summary: Tissue Location: Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Protein SCO1 homolog, mitochondrial, SCO1, SCOD1