Description
SCP2 Polyclonal Antibody | E-AB-52211 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: DKFZp686C12188, DKFZp686D11188, NLTP, NLTP, Non-specific lipid-transfer protein, Nonspecific lipid transfer protein, NSL TP, NSL-TP, OTTHUMP00000010488, OTTHUMP00000231766, OTTHUMP00000231767, OTTHUMP00000231768, OTTHUMP00000231769, OTTHUMP00000231770, OTTHUMP00000231772, OTTHUMP00000231773, OTTHUMP00000231774, OTTHUMP00000231776, OTTHUMP00000234662, Propanoyl CoA C acyltransferase, Propanoyl-CoA C-acyltransferase, SCP 2, SCP chi , SCP X, SCP-2, SCP-chi, SCP-X, SCP2, SCPchi , SCPX, Sterol carrier protein 2, Sterol carrier protein X
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal transduction
Background: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human SCP2
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 59 kDa
Molecular Weight(Observed): Refer to figures