SEC24C Antibody (Center) [AMM07743G]

SEC24C Antibody (Center) [AMM07743G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SEC24C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-470 amino acids from the Central region of human SEC24C.

Cellular Localisation: Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol

Molecular Weight: 118325

Clone: Polyclonal

Gene Name: SEC24C (HGNC:10705)

Gene ID: 9632

Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) . The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:10214955, PubMed:17499046, PubMed:18843296, PubMed:20427317) . Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296) . May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317) . May also be specific for IxM motif- containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296) .

Summary: Tissue Location: Ubiquitous..

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein transport protein Sec24C, SEC24-related protein C, SEC24C, KIAA0079