SEC31A Polyclonal Antibody | E-AB-68016

SEC31A Polyclonal Antibody | E-AB-68016 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: SEC31A, ABP125, ABP130, HSPC275, HSPC334, SEC31L1

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human SEC31A (NP_055748.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 56 kDa/105-134 kDa

Molecular Weight(Observed): 165 kDa