SEMA4A Antibody (N-term) [APR13242G]

SEMA4A Antibody (N-term) [APR13242G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This SEMA4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human SEMA4A.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein

Molecular Weight: 83574

Clone: Polyclonal

Gene Name: SEMA4A

Gene ID: 64218

Function: Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling (By similarity) . Regulates glutamatergic and GABAergic synapse development (By similarity) . Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner (By similarity) . Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T- helper cells, and thereby contributes to adaptive immunity (By similarity) . Promotes phosphorylation of TIMD2 (By similarity) . Inhibits angiogenesis (By similarity) . Promotes axon growth cone collapse (By similarity) . Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:500 WB--1:1000

Synonyms: Semaphorin-4A, Semaphorin-B, Sema B, SEMA4A, SEMAB, SEMB