SEMA4C Antibody (C-term) [APR13247G]

SEMA4C Antibody (C-term) [APR13247G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SEMA4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 792-821 amino acids of human SEMA4C.

Cellular Localisation: Cell junction, synapse, postsynaptic density membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein

Molecular Weight: 92623

Clone: Polyclonal

Gene Name: SEMA4C

Gene ID: 54910

Function: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity) . Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: FC, WB

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Semaphorin-4C, SEMA4C, KIAA1739, SEMAI