SEMA4D Polyclonal Antibody | E-AB-52208

SEMA4D Polyclonal Antibody | E-AB-52208 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: A8, BB 18, BB18, CD 100, CD100, CD100 antigen, Coll 4, COLL4, Collapsin 4, Collapsin4, GR3, Leukocyte activation antigen CD100, M sema G, MSEMA, SEM4D, Sema 4d, Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D, Sema H, SEMA J, Sema4d, Semacl 2, Semacl2, SemaH, SEMAJ, Semaphorin 4D, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semaphorin4D, SemaphorinJ, Semcl 2, Semcl2

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology, Neuroscience

Background: Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human SEMA4D

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A