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SENP8 (T191) polyclonal Antibody | BS1475
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- BW-BS1475
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Description
SENP8 (T191) polyclonal Antibody | BS1475 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC
Application Range: IHC: 1:50~1:200
Background: SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SENP8 (T191) polyclonal Antibody detects endogenous levels of SENP8 protein.
Molecular Weight: ~ 27 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Sentrin-specific protease 8; Deneddylase-1; NEDD8-specific protease 1; Protease, cysteine 2; Sentrin/SUMO-specific protease SENP8; SENP8; DEN1; NEDP1; PRSC2; FKSG8
Immunogen: Synthetic peptide, corresponding to amino acids 158-216 of Human SENP8.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: