SEPT11 Antibody (Center) [APR13263G]

SEPT11 Antibody (Center) [APR13263G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SEPT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-382 amino acids from the Central region of human SEPT11.

Cellular Localisation: Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria

Molecular Weight: 49398

Clone: Polyclonal

Gene Name: SEPTIN11 (HGNC:25589)

Gene ID: 55752

Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential) . May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity) . During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.

Summary: Tissue Location: Widely expressed, except in leukocytes.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Septin-11, SEPT11