SEPT7 Polyclonal Antibody | E-AB-11062

SEPT7 Polyclonal Antibody | E-AB-11062 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CDC10, CDC10 protein homolog, CDC3, Cell division cycle 10, NBLA02942, SEPT7, SEPT7, SEPT7A, Septin 7, Septin-7

Application: WB, IHC, ELISA

Reactivity: Human , Mouse , Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology

Background: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human SEPT7

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 51 kDa

Molecular Weight(Observed): Refer to figures